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Trypanosomes enter the human body through the feces of bedbugs, during a bite, or when scratching the skin and mucous membranes near the bite site.

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There is no effective treatment for Chagas disease. Drugs reduce lethality, but do not give confidence that tolerated doses will destroy parasites localized intracellularly.

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For the treatment of the acute stage, nifurtrimox and benznidazole are used. These same drugs are used in the early stages of the chronic phase.

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It is believed that chronic organ damage in Chagas disease is irreversible.

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To prevent it is recommended: avoid bedbug habitats (old, dilapidated dwellings), treat premises and clothing with special means, be wary of blood transfusions in countries at risk.

Chagas disease in Russia: symptoms and treatment. Chagas disease (American trypanosomiasis) is a pathology with an infectious etiology.

Chagas disease occurs in two stages.

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This ailment was first classified by Dr. K. Chagas. Currently, almost 18 million people of different age groups have this pathology. According to statistics maintained by many medical institutions around the world, almost 40,000 patients die every year from this protozoal infection. After the transition of the disease to the chronic stage, patients develop serious complications.

Patients may experience the following pathologies: The main danger of Chagas disease is that the primary infection in most cases is asymptomatic. As a result, people do not seek medical help in time, and doctors often give a disappointing prognosis for them. Characteristics of the pathogen.

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It has a spindle-shaped body, an undulating membrane and a flagellum.

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Trypanosomes after penetration into the body of a mammal or a person begin to conduct active parasitic activity. Their life cycle consists of several stages: At each stage of this infectious disease, patients may show different symptoms. In this category of patients, various signs of pathology can be observed, which significantly complicates the diagnostic process, since specialists have to differentiate this disease from other diseases.

Modern medicine knows three stages in the development of a protozoal transmissible infection: This stage lasts no more than 3 weeks. Symptoms of Chagas disease: immediately after the penetration of the parasite under the skin, erythematous nodules and swelling may appear. Patients develop conjunctivitis, redness is observed at the bite sites.

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In most cases, human infection occurs throughditch.

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The temperature rises. Fever develops. Edema appears, which is localized in the face and in the upper and lower extremities. Tissue infiltration occurs. A severe headache develops. Allergic rashes characteristic of urticaria or dermatitis appear on the skin. Patients experience difficulty in swallowing. Pathologies such as arrhythmia, hepatosplenomegaly, cardiomyopathy develop. Irreversible changes occur in the nervous system. Patients experience pain in the lower and upper limbs, in the articular and muscle tissues. The organs of vision, the corners of the lips and places typical of insect bites become inflamed.

Dysfunction in muscle tissues is observed. The work of the heart is disturbed, as a result of which lymphadenitis develops. There are degenerative changes in various internal organs. Articular pathologies develop. If a pregnant woman falls ill, she may give birth to a stillborn child or begin premature birth. In babies, hemorrhages in the meninges can occur. There is a possibility of sudden death.

The parasite can enter the human body when it comes into contact with open mucous membranes. Infection can also occur through products on which bedbug feces are found. This stage lasts no more than 3 months. In the primary phase of the disease, the parasites move through the bloodstream, so in most cases there are no symptoms. In this phase of the pathology, a total infection of dapsone pills.

 

 

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  • In the chronic form of a protozoal vector-borne infection, patients may experience the following symptoms:
  • To diagnose a protozoal vector-borne infection, specialists take the following actions:
  • Patients are prescribed general tests. Carrier xenodiagnosis is performed. Patients hand over punctures from the places of the primary lesion.

In patients, cerebrospinal fluid is taken. Specialists surgically collect biological material from the lymph nodes, bone marrow, and spleen. If a patient is suspected of having a chronic form of dapsone, then laboratory mice are used to isolate antigens, which they deliberately infect.

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Despite the fact that modern medicine has stepped far ahead and uses innovative methods and the latest pharmacological developments in the treatment of complex pathologies, it cannot fully cope with Chagas disease. The use of dapsone drugs in the process of drug therapy can reduce the mortality rate among the infected population. At the same time, not a single modern drug is able to completely rid the patient's body of parasites.

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When conducting drug therapy, specialists use complex antiparasitic drugs, the action of which is aimed at relieving symptoms. Also, in the fight against this disease, immunostimulants are used that can increase the body's resistance to this parasitic infection.

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